Articles tagged "nonobody"

The 16th European Microscopy Congress 2016
Structural basis of Nanobody-mediated plant virus resistance and vector transmission revealed by cryo-EM.
Caroline Hemmer (1, 2), Igor Orlov (3), Léa Ackerer (1, 2, 4), Aurélie Marmonier (2), Kamal Hleibieh (1), Corinne Schmitt-Keichinger (1), Emmanuelle Vigne (2), Sophie Gersch (2), Véronique Komar (2), Lorène Belval (2), François Berthold (1), Baptiste Monsion (1), Patrick Bron (5), Olivier Lemaire (2), Bernard Lorber (6), Carlos Gutiérrez (7), Serge Muyldermans (8), Gérard Demangeat (2), Bruno Klaholz (3), Christophe Ritzenthaler (1)
1. Institut de biologie moléculaire des plantes du CNRS, Université de Strasbourg, Strasbourg, France 2. Institut national de la recherche agronomique, UMR 1131, Colmar, France 3. Centre de Biologie Intégrative, Institut de génétique et de biologie moléculaire et cellulaire, CNRS UMR 7104-Inserm U964, Illkirch, France 4. Institut Français de la Vigne et du Vin, Le Grau du Roi, France 5. Centre de Biochimie Structurale, CNRS UMR 5048, INSERM UMR 1054, University of Montpellier, Montpellier, France 6. Institut de biologie moléculaire et cellulaire, CNRS, Strasbourg, France 7. Department of Animal Medicine and Surgery, Veterinary Faculty, University of Las Palmas de Gran Canaria, Arucas, Las Palmas, Espagne 8. Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgique
Since their discovery, single-domain antigen-binding fragments of camelid-derived heavy chain-only antibodies, also known as Nanobodies (Nbs), have proven to be of outstanding interest as therapeutics…