Articles tagged "Huntington’s disease"

The 16th European Microscopy Congress 2016
Three-dimensional maps of full-length huntingtin and linkage to development of Huntington’s disease
Taeyang Jung (1, 2, 3), Ihnsik Seong (4), Ji-Joon Song (5), Hans Hebert (1, 2)
1. Department of Biosciences, Karolinska Institutet, Huddinge, Suède 2. School of Technology and Health, KTH Royal Institute of Technology, Huddinge, Suède 3. Department of Biological Sciences, Korean Advanced Institute of Technology and Health, Daejeon, Corée du Sud 4. Department of Neurology, Harvard Medical School, Boston, Etats-Unis 5. Department of Biological Sciences, Korean Advanced Institute of Science and Technology, Daejeon, Corée du Sud
Among neurodegenerative diseases causing serious medical and social problems, in particular in association with an aging population, Huntington´s disease (HD) is classified as a representative…
The 16th European Microscopy Congress 2016
Organelle changes in a Huntington’s disease model using cryogenic soft x-ray tomography
Michele Darrow (1), Wei Dai (2), Patrick Mitchell (3, 4), Imanol Luengo (5), Wah Chiu (4), Elizabeth Duke (1)
1. Life Science, Diamond Light Source, Harwell, Royaume Uni 2. Department of Cell Biology and Neuroscience, and Center for Integrative Proteomics Research, Rutgers University, New Jersey, Etats-Unis 3. Integrative Molecular and Biomedical Sciences Program, Baylor College of Medicine, Houston, Etats-Unis 4. National Center for Macromolecular Imaging , Baylor College of Medicine, Houston, Etats-Unis 5. The University of Nottingham, Nottingham, Royaume Uni
Huntington’s Disease, a neurodegenerative disorder characterized by movement and executive function disruption, is linked to an expanded and unstable CAG trinucleotide repeat which translates as…