Articles tagged "cystic fibrosis"

The 16th European Microscopy Congress 2016
The supramolecular packing of the gel-forming MUC5B and MUC2 mucins and its importance for cystic fibrosis
Harriet E. Nilsson (1, 2), Sergio Muyo Trillo (2), Anna Ermund (2), Malin Bäckström (2, 3), Elisabeth Thomsson (3), Daniel Ambort (2), Philip J. B. Koeck (1, 4), David J. Thornton (5), Gunnar C. Hansson (2), Hans Hebert (1, 4)
1. Dept of bioscience and nutrition, Karolinska Institutet, Novum, Huddinge, Suède 2. Medical Biochemistry, University of Gothenburg, Göteborg, Suède 3. Mammalian Protein Expression Core Facility, University of Gothenburg, Göteborg, Suède 4. School of Technology and Health, KTH Royal Institute of Technology, Huddinge, Suède 5. Wellcome Trust Centre for Cell-Matrix Research, University of Manchester, Manchester, Royaume Uni
Text: Introduction: The genetically related gel forming mucins, MUC2 (intestine), MUC5B (airways), MUC5AC (airways, stomach) and MUC6 (stomach) have large sizes with heavily glycosylated mucin…