The 16th European Microscopy Congress 2016
New developments in direct electron detecting cameras and their importance for cryo-EM.
1. Structural Studies Division, MRC laboratory of Molecular Biology, Cambridge, Royaume Uni
Direct electron detectors have played a key role in the recent increase in the power of single particle electron cryomicroscopy (cryo-EM). In this talk, I…The 16th European Microscopy Congress 2016
A versatile high-vacuum cryo transfer system for cryo microscopy and analytics
The conservation of the native state during sample preparation is mandatory for a correct interpretation of any micrograph. Particularly for EM, the preservation of the…The 16th European Microscopy Congress 2016
The interior of the rotavirus capsid
1. Methods in electron microscopy (MEM), Institut de Biologie Structurale, Grenoble, France
Rotavirus and other double-stranded RNA viruses confine and protect their genome inside the capsid even after cell entry, hiding viral ds-RNA from the cellular immune…The 16th European Microscopy Congress 2016
High resolution cryo-EM of eukaryotic proteasomes: an emerging tool for therapeutic drug development
1. MRC Laboratory of Molecular Biology, -, Cambridge, Royaume Uni
Recently the field of biological structural electron microscopy has seen an enormous transformation, primarily triggered by the availability of improved electron microscopes and direct electron…The 16th European Microscopy Congress 2016
Our muscle at near-atomic resolution – Cryo-EM structure of the F-actin-tropomyosin complex.
Muscular movement plays an essential role not only in our lives but also describes a fundamental mechanism of force production. Filamentous actin (F-actin) is the major…The 16th European Microscopy Congress 2016
Structure-function insights reveal the human ribosome as a cancer target for antibiotics
Abstract Many antibiotics in clinical use target the bacterial ribosome by interfering with several mechanistic steps of the protein synthesis machinery. However, targeting the human…The 16th European Microscopy Congress 2016
Cryo-EM Structural characterization of the M. tuberculosis ESX-1 secreted virulence factor EspB
Mycobacterium tuberculosis (Mtb) is the top infectious disease killer worldwide. The threat posed by this bacterium is higher than ever, with the recent discovery of…The 16th European Microscopy Congress 2016
Fusion to a symmetric scaffold allows cryo-EM analysis of a small monomeric protein
Single particle cryo-electron microscopy (cryoEM) is a powerful method for determining the structures of large macromolecules and their complexes. Recent technical advances in direct electron…The 16th European Microscopy Congress 2016
Structure of the bacterial type 3 secretion system in action
Pathogenic bacteria commonly use the conserved type 3 secretion system (T3SS or Injectisome) to deliver virulence factors into the target eukaryotic cells in order to…
Official abstracts site for the European Microscopy Congress