The 16th European Microscopy Congress 2016
EELS analysis of the interaction betweeen frozen acqueous samples and incident electrons in TEM
Radiation damage is a major limiting factor in obtaining high resolution images in cryo-electron microscopy. Quantifying and understanding those radiation damages are considerable challenges. While…The 16th European Microscopy Congress 2016
Cryo-electron microscopy structure of La Crosse orthobunyavirus polymerase in presence or absence of viral RNA
Bunyaviridae is the largest family of segmented negative strand viruses (sNSV) which also include Orthomyxoviridae and Arenaviridae. Central to their viral cycle is the RNA-dependent…The 16th European Microscopy Congress 2016
Structural basis of Nanobody-mediated plant virus resistance and vector transmission revealed by cryo-EM.
Since their discovery, single-domain antigen-binding fragments of camelid-derived heavy chain-only antibodies, also known as Nanobodies (Nbs), have proven to be of outstanding interest as therapeutics…The 16th European Microscopy Congress 2016
Structure of filamentous alternanthera mosaic virus and mechanism of its activation.
Alternanthera mosaic virus (AltMV) is a filamentous plant virus belonging to the genus Potexvirus. The virus contains a single-strand RNA and coat protein (CP) that…The 16th European Microscopy Congress 2016
The near-atomic resolution cryo electron microscopy structure of the lactococcal siphophage 1358 virion mature full capsid.
Lactococcus lactis, a Gram(+) lactic acid-producing bacterium used for the manufacture of several fermented dairy products, is subject to infection by diverse virulent tailed phages,…The 16th European Microscopy Congress 2016
Self-assembly characterization of Saccaharomyces Cerevisiae and Drosophila Melanogaster septins by cryo-electron microscopy and tomography
1. UMR 168, Institut Curie, paris, France
Septins are a highly conserved1 family of proteins in eukaryotes required for cell division. These proteins are recognized as the fourth component of the cytoskeleton.…The 16th European Microscopy Congress 2016
Single particle EM study of the E1 helicase from Papillomavirus in complex with DNA
The papillomaviruses (PV) are small dsDNA tumour viruses of significant medical importance and the prototype of the group is bovine PV (BPV-1). PVs encode one…The 16th European Microscopy Congress 2016
Structural insight into the function of full-length human Fanconi Anemia FANCD2/FANCI complex by cryo-electron microscopy
1. INTRODUCTION At the center of the DNA damage Fanconi Anemia repair pathway is the FANCD2/FANCI complex, which is monoubiquitinated upon DNA damage, and this…The 16th European Microscopy Congress 2016
Structure of an elongation factor G-ribosome complex captured in the absence of any inhibitor
1. Translation and Folding Team, UMR CNRS 6290 IGDR, Rennes, France
The ribosome is a large molecular machine performing protein synthesis (translation) in all living cells. During the elongation cycle of protein synthesis, new amino acids…The 16th European Microscopy Congress 2016
Local order and conformation of nucleosomes in solution and in interphase nuclei analysed by cryo-electron microscopy of vitreous sections
Despite spectacular advances in our knowledge of chromosome dynamics and large scale organisation, little is still known about how the 10 nm nucleosome bead-on-string fibre…