Articles tagged "cardiac muscle"

The 16th European Microscopy Congress 2016
Synchrotron Infrared Microspectroscopy, an innovative approach to investigate tissue chemical changes in mouse model of Pompe of disease (glycogenosis type II) and to assess efficiency in gene therapy.
Laurence Dubreil (1, 2), Juliette Hordeaux (1, 2), Johan Deniaud (1, 2), Lydie Lagalice (1, 2), Karim Bey (1, 2), Christophe Sandt (3), Frederic Jamme (4), Marie-Anne Colle (1, 2)
1. INRA UMR U703, Animal Pathophysiology and Biotherapy for Muscle and Nervous system Diseases, INRA Oniris, Nantes, France 2. LUNAM Université, Oniris, École nationale vétérinaire, agro-alimentaire et de l’alimentation Nantes-Atlantique, Nantes, F-44307, France, Oniris, Nantes, France 3. SMIS beamline, SOLEIL, French national synchrotron facility, Gif-sur-Yvette, France 4. DISCO beamline, SOLEIL, French national synchrotron facility, Gif-sur-Yvette, France
Pompe disease is an autosomal recessive disorder caused by the deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA). The disease is characterized by lysosomal glycogen…